In this description of the stratification/lamination of the subiculum, the most superficial layer, close to the pial surface of the brain comes first, followed by the layers below.
- The most superficial layer is referred to as the molecular layer or stratum moleculare and this layer is divided in a superficial and a deep part. The superficial stratum moleculare in the subiculum is a continuation of the molecular layer that runs between CA1 and the presubiculum. The deep stratum moleculare on the other hand, runs as a continuation of the stratum radiatum. (see e.g. Blackstad, 1956)
- The pyramidal cell layer or stratum pyramidale. The border with CA1 is determined by an abrubt wideing of the this layer, abrubt loss of staining in calbindin stained material and increased staining in Timm stained material. The border with the presubiculum is harder to detect, but a noticable decrease in the size of pyramidal cells can be observerd in layers II/III of the presubiculum.
- The stratum oriens, although present in the rest of the cornu ammonus, is not present in the subiculum.
Boccara, C. N., Kjonigsen, L. J., Hammer, I. M., Bjaalie, J. G., Leergaard, T. B., & Witter, M. P. (2015). . A three-plane architectonic atlas of the rat hippocampal region. Hippocampus, 25(7), 838–857. Subiculum in Hippocampus Atlas
Cappaert, N. L. M., Van Strien, N. M., & Witter, M. P. (2015). Chapter 20 - Hippocampal Formation. In G. Paxinos (Ed.), The Rat Nervous System (Fourth Edition) (pp. 511–573). San Diego: Academic Press.
Blackstad, T. W. (1956). Commissural connections of the hippocampal region in the rat, with special reference to their mode of termination. The Journal of Comparative Neurology, 105(3), 417–537. Resolve DOI